http://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&feed=atom&action=historyВідділ молекулярної біофізики - Історія редагувань2024-03-29T09:36:47ZІсторія редагувань цієї сторінки в вікіMediaWiki 1.18.1http://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12432&oldid=prevPasha: /* Recent References */2020-02-25T17:41:08Z<p><span class="autocomment">Recent References</span></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Delmas P, Korogod S, Coste B. Biophysical mechanisms of pathological activity of neurons related to hypoxia-ischemic and inflammatory injuries. In: Noxious Mechanosensation The Oxford Handbook of the Neurobiology of Pain. (2018). DOI:10.13989/j.cnki.0517-6611.2015.11.042</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Delmas P, Korogod S, Coste B. Biophysical mechanisms of pathological activity of neurons related to hypoxia-ischemic and inflammatory injuries. In: Noxious Mechanosensation The Oxford Handbook of the Neurobiology of Pain. (2018). DOI:10.13989/j.cnki.0517-6611.2015.11.042</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Savchenko A, Cherkas V, Liu C, Braun GB, Kleschevnikov A, Miller YI, et al. Graphene biointerfaces for optical stimulation of cells. Sci Adv. 4(5):eaat0351 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29795786 PMID:29795786]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12428&oldid=prevPasha: /* Recent References */2020-02-25T17:26:12Z<p><span class="autocomment">Recent References</span></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Bos R, Harris-Warrick RM, Brocard C, Demianenko LE, Manuel M, Zytnicki D, et al. Kv1.2 Channels Promote Nonlinear Spiking Motoneurons for Powering Up Locomotion. Cell Rep. 22(12):3315–27 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29562186 PMID:29562186]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Bos R, Harris-Warrick RM, Brocard C, Demianenko LE, Manuel M, Zytnicki D, et al. Kv1.2 Channels Promote Nonlinear Spiking Motoneurons for Powering Up Locomotion. Cell Rep. 22(12):3315–27 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29562186 PMID:29562186]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Delmas P, Korogod S, Coste B. Biophysical mechanisms of pathological activity of neurons related to hypoxia-ischemic and inflammatory injuries. In: Noxious Mechanosensation The Oxford Handbook of the Neurobiology of Pain. (2018). DOI:10.13989/j.cnki.0517-6611.2015.11.042</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12427&oldid=prevPasha: /* Recent References */2020-02-25T17:22:31Z<p><span class="autocomment">Recent References</span></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Gryshchenko O, Gerasimenko J V, Peng S, Gerasimenko O V, Petersen OH. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 596(14):2663–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29424931 PMID:29424931]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Gryshchenko O, Gerasimenko J V, Peng S, Gerasimenko O V, Petersen OH. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 596(14):2663–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29424931 PMID:29424931]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Bos R, Harris-Warrick RM, Brocard C, Demianenko LE, Manuel M, Zytnicki D, et al. Kv1.2 Channels Promote Nonlinear Spiking Motoneurons for Powering Up Locomotion. Cell Rep. 22(12):3315–27 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29562186 PMID:29562186]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12425&oldid=prevPasha: /* References */2020-02-25T17:14:18Z<p><span class="autocomment">References</span></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Continuing this research we have recently found that complete Freund adjuvant (CFA)-induced peripheral inflammation, a well-known model of chronic inflammatory pain, prominently augments excitatory neurotransmission in rat dorsal horn lamina II neurons exhibiting adapting firing patterns (Kopach et al., 2015) and apparently representing excitatory glutamatergic interneurons. At the same time this peripheral inflammation decreases excitatory drive to the tonic firing lamina II neurons most of which are inhibitory. The inhibitory drive is also increased to the inhibitory neurons and decreased to the excitatory ones as a result of the inflammation (Kopach et al., 2015). Thus, the balance between excitation and inhibition in the lamina II of dorsal horn is strongly shifted toward the excitation (Kopach et al., 2015). The lamina II interneurons directly synapse onto lamina I projection neurons (PNs), the main output of painful signaling in the spinal cord. Thus, these inflammatory-induced, neuron-type specific changes in synaptic activity in lamina II neurons most probably results in an increase of the excitatory drive and a decrease of the inhibitory drive to lamina I PNs. In its turn it may increase PN excitability, hence contributing to maintenance of the inflammatory pain. In this research we aim to test this hypothesis and to study what cellular and molecular mechanisms underlie increased excitability of PNs under inflammatory conditions.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Continuing this research we have recently found that complete Freund adjuvant (CFA)-induced peripheral inflammation, a well-known model of chronic inflammatory pain, prominently augments excitatory neurotransmission in rat dorsal horn lamina II neurons exhibiting adapting firing patterns (Kopach et al., 2015) and apparently representing excitatory glutamatergic interneurons. At the same time this peripheral inflammation decreases excitatory drive to the tonic firing lamina II neurons most of which are inhibitory. The inhibitory drive is also increased to the inhibitory neurons and decreased to the excitatory ones as a result of the inflammation (Kopach et al., 2015). Thus, the balance between excitation and inhibition in the lamina II of dorsal horn is strongly shifted toward the excitation (Kopach et al., 2015). The lamina II interneurons directly synapse onto lamina I projection neurons (PNs), the main output of painful signaling in the spinal cord. Thus, these inflammatory-induced, neuron-type specific changes in synaptic activity in lamina II neurons most probably results in an increase of the excitatory drive and a decrease of the inhibitory drive to lamina I PNs. In its turn it may increase PN excitability, hence contributing to maintenance of the inflammatory pain. In this research we aim to test this hypothesis and to study what cellular and molecular mechanisms underlie increased excitability of PNs under inflammatory conditions.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>==='''References'''===</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>==='''<ins class="diffchange diffchange-inline">Recent </ins>References'''===</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. 9(1):19231 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. 9(1):19231 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Kao, S.-C. C., Petralia, R. S., Belan, P., Tao, Y.-X. X. & Voitenko, N. Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn. Pain 152, 912–23 (2011). [http://www.ncbi.nlm.nih.gov/pubmed/21282008 PMID:21282008]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Kao, S.-C. C., Petralia, R. S., Belan, P., Tao, Y.-X. X. & Voitenko, N. Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn. Pain 152, 912–23 (2011). [http://www.ncbi.nlm.nih.gov/pubmed/21282008 PMID:21282008]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Dovgan, a V, Cherkas, V. P., Stepanyuk, a R., Fitzgerald, D. J., Haynes, L. P., Tepikin, a V, Burgoyne, R. D. & Belan, P. V. Decoding glutamate receptor activation by the Ca2+ sensor protein hippocalcin in rat hippocampal neurons. Eur. J. Neurosci. 32, 347–58 (2010). [http://www.ncbi.nlm.nih.gov/pubmed/20704590 PMID:20704590]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Dovgan, a V, Cherkas, V. P., Stepanyuk, a R., Fitzgerald, D. J., Haynes, L. P., Tepikin, a V, Burgoyne, R. D. & Belan, P. V. Decoding glutamate receptor activation by the Ca2+ sensor protein hippocalcin in rat hippocampal neurons. Eur. J. Neurosci. 32, 347–58 (2010). [http://www.ncbi.nlm.nih.gov/pubmed/20704590 PMID:20704590]</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Belan, P., Gardner, J., Gerasimenko, O., Gerasimenko, J., Mills, C. L., Petersen, O. H. & Tepikin, A. V. Isoproterenol evokes extracellular Ca2+ spikes due to secretory events in salivary gland cells. J. Biol. Chem. 273, 4106–4111 (1998). [http://www.ncbi.nlm.nih.gov/pubmed/9606103 PMID:9606103]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Gerasimenko, O. V., Gerasimenko, J. V., Belan, P. V. & Petersen, O. H. Inositol trisphosphate and cyclic ADP-ribose-mediated release of Ca2+ from single isolated pancreatic zymogen granules. Cell 84, 473–480 (1996). [http://www.ncbi.nlm.nih.gov/pubmed/8608601 PMID:8608601]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Belan, P. V, Gerasimenko, O. V, Tepikin, a V & Petersen, O. H. Localization of Ca2+ extrusion sites in pancreatic acinar cells. J. Biol. Chem. 271, 7615–9 (1996). [http://www.ncbi.nlm.nih.gov/pubmed/8631796 PMID:8631796]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Belan, P., Kostyuk, P., Snitsarev, V. & Tepikin, A. Calcium clamp in isolated neurones of the snail Helix pomatia. J. Physiol. 462, 47–58 (1993). [http://www.ncbi.nlm.nih.gov/pubmed/8392572 PMID:8392572]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Tepikin, A. V, Kostyuk, P. G., Snitsarev, V. A. & Belan, P. V. Extrusion of calcium from a single isolated neuron of the snail Helix pomatia. J. Membr. Biol. 123, 43–7 (1991). [http://www.ncbi.nlm.nih.gov/pubmed/1774773 PMID:1774773]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Members'''==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Members'''==</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12423&oldid=prevPasha: /* References */2020-02-25T17:02:49Z<p><span class="autocomment">References</span></p>
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<td colspan='2' style="background-color: white; color:black;">Версія за 17:02, 25 лютого 2020</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. <del class="diffchange diffchange-inline">1–12 </del>(2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. <ins class="diffchange diffchange-inline">9(1):19231 </ins>(2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12421&oldid=prevPasha: /* References */2020-02-25T17:01:17Z<p><span class="autocomment">References</span></p>
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<td colspan='2' style="background-color: white; color:black;">Версія за 17:01, 25 лютого 2020</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Gryshchenko O, Gerasimenko J V, Gerasimenko O V, Petersen OH. Calcium signalling in pancreatic stellate cells: Mechanisms and potential roles. Cell Calcium 59(2–3):140–4 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=26960936 PMID:26960936]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12418&oldid=prevPasha: /* References */2020-02-25T16:57:54Z<p><span class="autocomment">References</span></p>
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<td colspan='2' style="background-color: white; color:black;">Версія за 16:57, 25 лютого 2020</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Gryshchenko O, Gerasimenko J V, Peng S, Gerasimenko O V, Petersen OH. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 596(14):2663–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29424931 PMID:29424931]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Gryshchenko O, Gerasimenko J V, Peng S, Gerasimenko O V, Petersen OH. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 596(14):2663–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29424931 PMID:29424931]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Krotov, V., Belan, P. & Voitenko, N. Inflammatory-induced changes in synaptic drive and postsynaptic AMPARs in lamina II dorsal horn neurons are cell-type specific. Pain 156, 428–38 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25599231 PMID:25599231]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Krotov, V., Belan, P. & Voitenko, N. Inflammatory-induced changes in synaptic drive and postsynaptic AMPARs in lamina II dorsal horn neurons are cell-type specific. Pain 156, 428–38 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25599231 PMID:25599231]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Duzhyy, D. E., Viatchenko-Karpinski, V. Y., Khomula, E. V, Voitenko, N. V & Belan, P. V. Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons. Mol. Pain 11, 29 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25986602 PMID:25986602]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Duzhyy, D. E., Viatchenko-Karpinski, V. Y., Khomula, E. V, Voitenko, N. V & Belan, P. V. Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons. Mol. Pain 11, 29 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25986602 PMID:25986602]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12417&oldid=prevPasha: /* References */2020-02-25T16:54:11Z<p><span class="autocomment">References</span></p>
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<td colspan='2' style="background-color: white; color:black;">Версія за 16:54, 25 лютого 2020</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. <del class="diffchange diffchange-inline">2019;</del>1–12. [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>* Agashkov K, Krotov V, Krasniakova M, Shevchuk D, Andrianov Y, Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. 1–12 <ins class="diffchange diffchange-inline">(2019)</ins>. [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & Voitenko, N. High-threshold primary afferent supply of spinal lamina X neurons. Pain 160, 1982–1988 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Gryshchenko O, Gerasimenko J V, Peng S, Gerasimenko O V, Petersen OH. Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology. J Physiol. 596(14):2663–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29424931 PMID:29424931]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently-labeled targets in living cells. PLoS One 13, e0194031 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Krotov, V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O. et al. HIF-1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Peng S, Gerasimenko J V, Tsugorka T, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* Peng S, Gerasimenko J V, Tsugorka TM, Gryshchenko O, Samarasinghe S, Petersen OH, et al. Galactose protects against cell damage in mouse models of acute pancreatitis. J Clin Invest. 128(9):3769–78 (2018). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29893744 PMID:29893744]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Krotov, V., Belan, P. & Voitenko, N. Inflammatory-induced changes in synaptic drive and postsynaptic AMPARs in lamina II dorsal horn neurons are cell-type specific. Pain 156, 428–38 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25599231 PMID:25599231]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Kopach, O., Krotov, V., Belan, P. & Voitenko, N. Inflammatory-induced changes in synaptic drive and postsynaptic AMPARs in lamina II dorsal horn neurons are cell-type specific. Pain 156, 428–38 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25599231 PMID:25599231]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Duzhyy, D. E., Viatchenko-Karpinski, V. Y., Khomula, E. V, Voitenko, N. V & Belan, P. V. Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons. Mol. Pain 11, 29 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25986602 PMID:25986602]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* Duzhyy, D. E., Viatchenko-Karpinski, V. Y., Khomula, E. V, Voitenko, N. V & Belan, P. V. Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons. Mol. Pain 11, 29 (2015). [http://www.ncbi.nlm.nih.gov/pubmed/25986602 PMID:25986602]</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=12412&oldid=prevPasha: /* References */2020-02-25T16:45:37Z<p><span class="autocomment">References</span></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==='''References'''===</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Kopach O</del>, <del class="diffchange diffchange-inline">Viatchenko-Karpinski </del>V, <del class="diffchange diffchange-inline">Atianjoh F</del>, <del class="diffchange diffchange-inline">Belan P</del>, <del class="diffchange diffchange-inline">Tao </del>Y, <del class="diffchange diffchange-inline">and </del>Voitenko N. <del class="diffchange diffchange-inline"> PKCα is required for inflammation</del>-<del class="diffchange diffchange-inline">induced trafficking </del>of <del class="diffchange diffchange-inline">extrasynaptic AMPA receptors in tonically firing </del>lamina <del class="diffchange diffchange-inline">II dorsal horn </del>neurons <del class="diffchange diffchange-inline">during the maintenance of persistent inflammatory pain</del>.<del class="diffchange diffchange-inline">The Journal of </del>Pain, <del class="diffchange diffchange-inline">14</del>(<del class="diffchange diffchange-inline">2</del>):<del class="diffchange diffchange-inline">182</del>-<del class="diffchange diffchange-inline">92</del>. (<del class="diffchange diffchange-inline">2013</del>). <del class="diffchange diffchange-inline">IF 4</del>,<del class="diffchange diffchange-inline">5</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Agashkov K</ins>, <ins class="diffchange diffchange-inline">Krotov </ins>V, <ins class="diffchange diffchange-inline">Krasniakova M</ins>, <ins class="diffchange diffchange-inline">Shevchuk D</ins>, <ins class="diffchange diffchange-inline">Andrianov </ins>Y, <ins class="diffchange diffchange-inline">Zabenko Y. Distinct mechanisms of signal processing by lamina I spino- parabrachial neurons. Sci Rep. 2019;1–12. [https://www.ncbi.nlm.nih.gov/pubmed/?term=31848358 PMID:31848358]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#</del>Kopach <del class="diffchange diffchange-inline">O</del>, <del class="diffchange diffchange-inline">Viatchenko</del>-<del class="diffchange diffchange-inline">Karpinski </del>V, <del class="diffchange diffchange-inline">Atianjoh F</del>, <del class="diffchange diffchange-inline">Belan P</del>, <del class="diffchange diffchange-inline">Tao Y</del>, and Voitenko N. <del class="diffchange diffchange-inline">PKCα is required for inflammation</del>-induced <del class="diffchange diffchange-inline">trafficking of extrasynaptic AMPA receptors </del>in <del class="diffchange diffchange-inline">tonically firing </del>lamina II dorsal horn neurons <del class="diffchange diffchange-inline">during the maintenance of persistent inflammatory pain</del>. <del class="diffchange diffchange-inline">The Journal of </del>Pain, <del class="diffchange diffchange-inline">14</del>(<del class="diffchange diffchange-inline">2</del>):<del class="diffchange diffchange-inline">182-92</del>. <del class="diffchange diffchange-inline">(2013)</del>. <del class="diffchange diffchange-inline">IF 4,5</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Osypenko, D. S. et al. Perturbed Ca2+-dependent signaling of DYT2 hippocalcin mutant as mechanism of autosomal recessive dystonia. Neurobiol. Dis. 132, 104529 (2019). [https://www.ncbi.nlm.nih.gov/pubmed/?term=31301343 PMID:31301343]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Khomula</del>, <del class="diffchange diffchange-inline">E</del>.<del class="diffchange diffchange-inline">V</del>., Viatchenko-Karpinski, V.Y., <del class="diffchange diffchange-inline">Borisyuk</del>, <del class="diffchange diffchange-inline">A.L</del>., <del class="diffchange diffchange-inline">Duzhyy D</del>, <del class="diffchange diffchange-inline">Belan, P</del>.V<del class="diffchange diffchange-inline">.</del>, <del class="diffchange diffchange-inline">Voitenko N</del>.V. <del class="diffchange diffchange-inline">Specific functioning </del>of <del class="diffchange diffchange-inline">Cav3.2 </del>T-type <del class="diffchange diffchange-inline">calcium and TRPV1 </del>channels <del class="diffchange diffchange-inline">under different types of STZ</del>-<del class="diffchange diffchange-inline">diabetic neuropathy  Biochimica et Biophysica Acta - Molecular Basis </del>of <del class="diffchange diffchange-inline">Disease</del>, <del class="diffchange diffchange-inline">1832</del>(<del class="diffchange diffchange-inline">5</del>):<del class="diffchange diffchange-inline">636–649</del>. <del class="diffchange diffchange-inline">(2013)</del>. <del class="diffchange diffchange-inline">IF 5,7</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Krotov, V., Tokhtamysh, A., Safronov, B. V., Belan, P. & </ins>Voitenko<ins class="diffchange diffchange-inline">, </ins>N. <ins class="diffchange diffchange-inline">High</ins>-<ins class="diffchange diffchange-inline">threshold primary afferent supply </ins>of <ins class="diffchange diffchange-inline">spinal </ins>lamina <ins class="diffchange diffchange-inline">X </ins>neurons. Pain <ins class="diffchange diffchange-inline">160</ins>, <ins class="diffchange diffchange-inline">1982–1988 </ins>(<ins class="diffchange diffchange-inline">2019</ins>)<ins class="diffchange diffchange-inline">. [https</ins>:<ins class="diffchange diffchange-inline">//www.ncbi.nlm.nih.gov/pubmed/?term=30985620 PMID:30985620]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#</del>Stepanyuk <del class="diffchange diffchange-inline">AR</del>, Borisyuk <del class="diffchange diffchange-inline">AL</del>, Tsugorka <del class="diffchange diffchange-inline">TM</del>, Belan <del class="diffchange diffchange-inline">PV </del>Different pools of postsynaptic GABAA receptors mediate inhibition evoked by <del class="diffchange diffchange-inline">low‐and high‐frequency </del>presynaptic stimulation at hippocampal synapses Synapse 68 (<del class="diffchange diffchange-inline">8</del>), <del class="diffchange diffchange-inline">344-354</del>. <del class="diffchange diffchange-inline">(2014</del>. <del class="diffchange diffchange-inline">IF 2</del>,<del class="diffchange diffchange-inline">9</del>)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Cherkas, V. et al. Measurement of intracellular concentration of fluorescently</ins>-<ins class="diffchange diffchange-inline">labeled targets in living cells</ins>. <ins class="diffchange diffchange-inline">PLoS One 13, e0194031 </ins>(<ins class="diffchange diffchange-inline">2018</ins>). <ins class="diffchange diffchange-inline">[https://www.ncbi.nlm.nih.gov/pubmed/?term=29694385 PMID:29694385]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#</del>Khomula, E.V., Borisyuk, A.L., <del class="diffchange diffchange-inline">Viatchenko-Karpinski</del>, <del class="diffchange diffchange-inline">V</del>.<del class="diffchange diffchange-inline">Y</del>.<del class="diffchange diffchange-inline">, Briede A</del>, Belan, P.V<del class="diffchange diffchange-inline">.</del>, <del class="diffchange diffchange-inline">Voitenko </del>N.V. <del class="diffchange diffchange-inline">Nociceptive neurons differentially express fast and slow </del>T-type <del class="diffchange diffchange-inline">Ca 2+ currents in </del>different types of diabetic neuropathy <del class="diffchange diffchange-inline"> Neural Plasticity</del>. <del class="diffchange diffchange-inline">Epub (2014)</del>. <del class="diffchange diffchange-inline">IF 3,6</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Krotov</ins>, <ins class="diffchange diffchange-inline">V. et al. Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation. Front. Cell. Neurosci. 11, 1–12 (2017). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Stepanyuk AR, Belan PV, Kononenko  A Model for the Fast Synchronous Oscillations of Firing Rate in Rat Suprachiasmatic Nucleus Neurons Cultured in a Multielectrode Array Dish</del>. <del class="diffchange diffchange-inline">PloS one 9 (9)</del>, <del class="diffchange diffchange-inline">e106152. </del>(<del class="diffchange diffchange-inline">2014</del>). <del class="diffchange diffchange-inline">IF 4,4</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* </ins>Kopach, <ins class="diffchange diffchange-inline">O. et al. HIF</ins>-<ins class="diffchange diffchange-inline">1α-mediated upregulation of SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular Ca(2+) store dysfunction in CA1 and CA3 hippocampal neurons. Cell Calcium 59, 251–61 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=29163053 PMID:29163053]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Stepanyuk A, Borisyuk A, Belan P  Maximum likelihood estimation of biophysical parameters of synaptic receptors from macroscopic currents</del>. <del class="diffchange diffchange-inline">Frontiers in cellular neuroscience 8, 303</del>. <del class="diffchange diffchange-inline">(2014)</del>. <del class="diffchange diffchange-inline">IF 4,6</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Peng S, Gerasimenko J </ins>V, <ins class="diffchange diffchange-inline">Tsugorka T</ins>, <ins class="diffchange diffchange-inline">Gryshchenko O</ins>, <ins class="diffchange diffchange-inline">Samarasinghe S</ins>, <ins class="diffchange diffchange-inline">Petersen OH, et al. Calcium </ins>and <ins class="diffchange diffchange-inline">adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2. Philos Trans R Soc Lond B Biol Sci [Internet]. 371(1700):20150423 (2016). [https://www.ncbi.nlm.nih.gov/pubmed/?term=27377732 PMID:27377732]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#</del>Kopach, O., <del class="diffchange diffchange-inline">Krotov</del>, <del class="diffchange diffchange-inline">V</del>., Belan, P., Voitenko, N. <del class="diffchange diffchange-inline"> Inflammatory-induced changes in synaptic drive and postsynaptic AMPARs </del>in lamina II dorsal horn <del class="diffchange diffchange-inline">neurons are cell-type specific</del>. Pain, <del class="diffchange diffchange-inline">156</del>(<del class="diffchange diffchange-inline">3</del>):<del class="diffchange diffchange-inline">428-38</del>.<del class="diffchange diffchange-inline">(2015)</del>. <del class="diffchange diffchange-inline">IF 5,6</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Kopach, O., Krotov, V., Belan, P. & </ins>Voitenko<ins class="diffchange diffchange-inline">, </ins>N. <ins class="diffchange diffchange-inline">Inflammatory</ins>-induced <ins class="diffchange diffchange-inline">changes in synaptic drive and postsynaptic AMPARs </ins>in lamina II dorsal horn neurons <ins class="diffchange diffchange-inline">are cell-type specific</ins>. Pain <ins class="diffchange diffchange-inline">156</ins>, <ins class="diffchange diffchange-inline">428–38 </ins>(<ins class="diffchange diffchange-inline">2015</ins>)<ins class="diffchange diffchange-inline">. [http</ins>:<ins class="diffchange diffchange-inline">//www</ins>.<ins class="diffchange diffchange-inline">ncbi</ins>.<ins class="diffchange diffchange-inline">nlm.nih.gov/pubmed/25599231 PMID:25599231]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Duzhyy</del>, <del class="diffchange diffchange-inline">D</del>.<del class="diffchange diffchange-inline">E</del>., <del class="diffchange diffchange-inline">Viatchenko-Karpinski</del>, <del class="diffchange diffchange-inline">V</del>.<del class="diffchange diffchange-inline">Y</del>., <del class="diffchange diffchange-inline">Khomula</del>, <del class="diffchange diffchange-inline">E</del>.<del class="diffchange diffchange-inline">V</del>., <del class="diffchange diffchange-inline">Voitenko</del>, <del class="diffchange diffchange-inline">N.</del>V<del class="diffchange diffchange-inline">.</del>, Belan, P.V. <del class="diffchange diffchange-inline">Upregulation of T-type Ca<sup>2</del>+<del class="diffchange diffchange-inline"></sup> channels </del>in <del class="diffchange diffchange-inline">long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG </del>neurons. <del class="diffchange diffchange-inline">Molecular Pain</del>. <del class="diffchange diffchange-inline">20;11</del>(<del class="diffchange diffchange-inline">1</del>):<del class="diffchange diffchange-inline">29</del>. <del class="diffchange diffchange-inline">(2015) IF 4,1</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Duzhyy</ins>, <ins class="diffchange diffchange-inline">D</ins>. <ins class="diffchange diffchange-inline">E</ins>., Viatchenko-Karpinski, V. Y., <ins class="diffchange diffchange-inline">Khomula</ins>, <ins class="diffchange diffchange-inline">E</ins>. <ins class="diffchange diffchange-inline">V</ins>, <ins class="diffchange diffchange-inline">Voitenko</ins>, <ins class="diffchange diffchange-inline">N</ins>. V <ins class="diffchange diffchange-inline">& Belan</ins>, <ins class="diffchange diffchange-inline">P</ins>. V. <ins class="diffchange diffchange-inline">Upregulation </ins>of T-type <ins class="diffchange diffchange-inline">Ca2+ </ins>channels <ins class="diffchange diffchange-inline">in long</ins>-<ins class="diffchange diffchange-inline">term diabetes determines increased excitability </ins>of <ins class="diffchange diffchange-inline">a specific type of capsaicin-insensitive DRG neurons. Mol. Pain 11</ins>, <ins class="diffchange diffchange-inline">29 </ins>(<ins class="diffchange diffchange-inline">2015</ins>)<ins class="diffchange diffchange-inline">. [http</ins>:<ins class="diffchange diffchange-inline">//www</ins>.<ins class="diffchange diffchange-inline">ncbi</ins>.<ins class="diffchange diffchange-inline">nlm.nih.gov/pubmed/25986602 PMID:25986602]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Kopach</del>, O., <del class="diffchange diffchange-inline">Maistrenko</del>, <del class="diffchange diffchange-inline">A</del>., <del class="diffchange diffchange-inline">Lushnikova</del>, <del class="diffchange diffchange-inline">I</del>., <del class="diffchange diffchange-inline">Belan P</del>, <del class="diffchange diffchange-inline">Skibo</del>, <del class="diffchange diffchange-inline">G</del>., <del class="diffchange diffchange-inline">Voitenko</del>, <del class="diffchange diffchange-inline">N</del>. <del class="diffchange diffchange-inline">HIF</del>-<del class="diffchange diffchange-inline">1α</del>-mediated <del class="diffchange diffchange-inline">upregulation </del>of <del class="diffchange diffchange-inline">SERCA2b: The endogenous mechanism for alleviating the ischemia-induced intracellular </del>Ca2+<del class="diffchange diffchange-inline">store dysfunction in CA1 and CA3 hippocampal neurons</del>. Cell <del class="diffchange diffchange-inline">Calcium. 59</del>(<del class="diffchange diffchange-inline">5</del>):<del class="diffchange diffchange-inline">251-61</del>. (<del class="diffchange diffchange-inline">2016</del>). <del class="diffchange diffchange-inline">IF 4,3</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* </ins>Stepanyuk<ins class="diffchange diffchange-inline">, A. R.</ins>, Borisyuk<ins class="diffchange diffchange-inline">, A. L.</ins>, Tsugorka, <ins class="diffchange diffchange-inline">T. M. & </ins>Belan<ins class="diffchange diffchange-inline">, P. V. </ins>Different pools of postsynaptic GABAA receptors mediate inhibition evoked by <ins class="diffchange diffchange-inline">low- and high-frequency </ins>presynaptic stimulation at hippocampal synapses<ins class="diffchange diffchange-inline">. </ins>Synapse 68<ins class="diffchange diffchange-inline">, 344–54 </ins>(<ins class="diffchange diffchange-inline">2014</ins>)<ins class="diffchange diffchange-inline">. [http://www.ncbi.nlm.nih.gov/pubmed/24677449 PMID:24677449]</ins></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">#Krotov </del>V, <del class="diffchange diffchange-inline">Tokhtamysh </del>A, <del class="diffchange diffchange-inline">Kopach O</del>, <del class="diffchange diffchange-inline">Dromaretsky </del>A, <del class="diffchange diffchange-inline">Sheremet Y</del>, <del class="diffchange diffchange-inline">Belan </del>P, <del class="diffchange diffchange-inline">Voitenko N</del>. <del class="diffchange diffchange-inline">Functional Characterization of Lamina X Neurons in ex-Vivo Spinal Cord Preparation</del>. <del class="diffchange diffchange-inline">Frontiers in cellular neuroscience 11</del>, <del class="diffchange diffchange-inline">342</del>. (<del class="diffchange diffchange-inline">2017</del>). <del class="diffchange diffchange-inline">IF 4</del>.<del class="diffchange diffchange-inline">6</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Stepanyuk</ins>, <ins class="diffchange diffchange-inline">A</ins>.<ins class="diffchange diffchange-inline">, Borisyuk, A</ins>. <ins class="diffchange diffchange-inline">& Belan</ins>, <ins class="diffchange diffchange-inline">P. Maximum likelihood estimation of biophysical parameters of synaptic receptors from macroscopic currents. Front. Cell. Neurosci. 8, 303 (2014</ins>)<ins class="diffchange diffchange-inline">. [http://www.ncbi.nlm.nih.gov/pubmed/25324721 PMID:25324721]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* </ins>Khomula, E. V<ins class="diffchange diffchange-inline">, Viatchenko-Karpinski, V. Y</ins>., Borisyuk, A. L., <ins class="diffchange diffchange-inline">Duzhyy</ins>, <ins class="diffchange diffchange-inline">D</ins>. <ins class="diffchange diffchange-inline">E</ins>., Belan, P. V <ins class="diffchange diffchange-inline">& Voitenko</ins>, N. V. <ins class="diffchange diffchange-inline">Specific functioning of Cav3.2 </ins>T-type <ins class="diffchange diffchange-inline">calcium and TRPV1 channels under </ins>different types of <ins class="diffchange diffchange-inline">STZ-</ins>diabetic neuropathy. <ins class="diffchange diffchange-inline">Biochim</ins>. <ins class="diffchange diffchange-inline">Biophys</ins>. <ins class="diffchange diffchange-inline">Acta 1832</ins>, <ins class="diffchange diffchange-inline">636–49 </ins>(<ins class="diffchange diffchange-inline">2013</ins>). <ins class="diffchange diffchange-inline">[http://www</ins>.<ins class="diffchange diffchange-inline">ncbi</ins>.<ins class="diffchange diffchange-inline">nlm</ins>.<ins class="diffchange diffchange-inline">nih.gov/pubmed/23376589 PMID:23376589]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* </ins>Kopach, O., <ins class="diffchange diffchange-inline">Kao</ins>, <ins class="diffchange diffchange-inline">S.-C. C., Petralia, R. S</ins>., Belan, P., <ins class="diffchange diffchange-inline">Tao, Y.-X. X. & </ins>Voitenko, N. <ins class="diffchange diffchange-inline">Inflammation alters trafficking of extrasynaptic AMPA receptors </ins>in <ins class="diffchange diffchange-inline">tonically firing </ins>lamina II <ins class="diffchange diffchange-inline">neurons of the rat spinal </ins>dorsal horn. Pain <ins class="diffchange diffchange-inline">152</ins>, <ins class="diffchange diffchange-inline">912–23 </ins>(<ins class="diffchange diffchange-inline">2011</ins>)<ins class="diffchange diffchange-inline">. [http</ins>:<ins class="diffchange diffchange-inline">//www</ins>.<ins class="diffchange diffchange-inline">ncbi</ins>.<ins class="diffchange diffchange-inline">nlm.nih.gov/pubmed/21282008 PMID:21282008]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Dovgan</ins>, <ins class="diffchange diffchange-inline">a V, Cherkas, V</ins>. <ins class="diffchange diffchange-inline">P</ins>., <ins class="diffchange diffchange-inline">Stepanyuk</ins>, <ins class="diffchange diffchange-inline">a R</ins>.<ins class="diffchange diffchange-inline">, Fitzgerald, D. J</ins>., <ins class="diffchange diffchange-inline">Haynes</ins>, <ins class="diffchange diffchange-inline">L</ins>. <ins class="diffchange diffchange-inline">P</ins>., <ins class="diffchange diffchange-inline">Tepikin</ins>, <ins class="diffchange diffchange-inline">a </ins>V, <ins class="diffchange diffchange-inline">Burgoyne, R. D. & </ins>Belan, P. V. <ins class="diffchange diffchange-inline">Decoding glutamate receptor activation by the Ca2</ins>+ <ins class="diffchange diffchange-inline">sensor protein hippocalcin </ins>in <ins class="diffchange diffchange-inline">rat hippocampal </ins>neurons. <ins class="diffchange diffchange-inline">Eur</ins>. <ins class="diffchange diffchange-inline">J. Neurosci. 32, 347–58 </ins>(<ins class="diffchange diffchange-inline">2010</ins>)<ins class="diffchange diffchange-inline">. [http</ins>:<ins class="diffchange diffchange-inline">//www</ins>.<ins class="diffchange diffchange-inline">ncbi.nlm.nih.gov/pubmed/20704590 PMID:20704590]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Belan, P., Gardner, J., Gerasimenko</ins>, O., <ins class="diffchange diffchange-inline">Gerasimenko</ins>, <ins class="diffchange diffchange-inline">J</ins>., <ins class="diffchange diffchange-inline">Mills</ins>, <ins class="diffchange diffchange-inline">C. L</ins>., <ins class="diffchange diffchange-inline">Petersen</ins>, <ins class="diffchange diffchange-inline">O. H. & Tepikin</ins>, <ins class="diffchange diffchange-inline">A</ins>. <ins class="diffchange diffchange-inline">V. Isoproterenol evokes extracellular Ca2+ spikes due to secretory events in salivary gland cells. J. Biol. Chem. 273</ins>, <ins class="diffchange diffchange-inline">4106–4111 (1998). [http://www.ncbi.nlm.nih.gov/pubmed/9606103 PMID:9606103]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Gerasimenko</ins>, <ins class="diffchange diffchange-inline">O</ins>. <ins class="diffchange diffchange-inline">V., Gerasimenko, J. V., Belan, P. V. & Petersen, O. H. Inositol trisphosphate and cyclic ADP</ins>-<ins class="diffchange diffchange-inline">ribose</ins>-mediated <ins class="diffchange diffchange-inline">release </ins>of Ca2+ <ins class="diffchange diffchange-inline">from single isolated pancreatic zymogen granules</ins>. Cell <ins class="diffchange diffchange-inline">84, 473–480 </ins>(<ins class="diffchange diffchange-inline">1996</ins>)<ins class="diffchange diffchange-inline">. [http</ins>:<ins class="diffchange diffchange-inline">//www</ins>.<ins class="diffchange diffchange-inline">ncbi.nlm.nih.gov/pubmed/8608601 PMID:8608601]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Belan, P. V, Gerasimenko, O. V, Tepikin, a V & Petersen, O. H. Localization of Ca2+ extrusion sites in pancreatic acinar cells. J. Biol. Chem. 271, 7615–9 </ins>(<ins class="diffchange diffchange-inline">1996</ins>). <ins class="diffchange diffchange-inline">[http://www.ncbi.nlm.nih.gov/pubmed/8631796 PMID:8631796]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Belan, P., Kostyuk, P., Snitsarev, </ins>V<ins class="diffchange diffchange-inline">. & Tepikin</ins>, A<ins class="diffchange diffchange-inline">. Calcium clamp in isolated neurones of the snail Helix pomatia. J. Physiol. 462</ins>, <ins class="diffchange diffchange-inline">47–58 (1993). [http://www.ncbi.nlm.nih.gov/pubmed/8392572 PMID:8392572]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">* Tepikin</ins>, A<ins class="diffchange diffchange-inline">. V</ins>, <ins class="diffchange diffchange-inline">Kostyuk</ins>, P<ins class="diffchange diffchange-inline">. G.</ins>, <ins class="diffchange diffchange-inline">Snitsarev, V</ins>. <ins class="diffchange diffchange-inline">A</ins>. <ins class="diffchange diffchange-inline">& Belan</ins>, <ins class="diffchange diffchange-inline">P</ins>. <ins class="diffchange diffchange-inline">V. Extrusion of calcium from a single isolated neuron of the snail Helix pomatia. J. Membr. Biol. 123, 43–7 </ins>(<ins class="diffchange diffchange-inline">1991</ins>). <ins class="diffchange diffchange-inline">[http://www</ins>.<ins class="diffchange diffchange-inline">ncbi.nlm.nih.gov/pubmed/1774773 PMID:1774773]</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Members'''==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Members'''==</div></td></tr>
</table>Pashahttp://biph.kiev.ua/uk?title=%D0%92%D1%96%D0%B4%D0%B4%D1%96%D0%BB_%D0%BC%D0%BE%D0%BB%D0%B5%D0%BA%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D0%BE%D1%97_%D0%B1%D1%96%D0%BE%D1%84%D1%96%D0%B7%D0%B8%D0%BA%D0%B8&diff=10538&oldid=prevAmor: /* Загальна інформація */2018-04-23T08:15:16Z<p><span class="autocomment">Загальна інформація</span></p>
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<td colspan='2' style="background-color: white; color:black;">← Попередня версія</td>
<td colspan='2' style="background-color: white; color:black;">Версія за 08:15, 23 квітня 2018</td>
</tr><tr><td colspan="2" class="diff-lineno">Рядок 1:</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Загальна інформація'''==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Загальна інформація'''==</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Лабораторія Молекулярної Біофізики була заснована в квітні 2012 року на базі дослідницької групи відділу <ins class="diffchange diffchange-inline">[</ins>[Department of General Physiology of Nervous System|Загальної Фізіології Нервової Системи<ins class="diffchange diffchange-inline">]</ins>], яка була керована Павлом Біланом<ins class="diffchange diffchange-inline">. Виокремлена у відділ в 2016 році</ins>. Головними предметами досліджень протягом останніх років були механізми регуляції внутрішньоклітинної концентрації Ca2+та кальцієва сигналізації в різних типах збудливих клітин.В експериментах використовуються нейрони, які є ізольованими або знаходяться в культурі, а також зрізи мозкута інтактний спинний мозок.В наших дослідженнях ми застосовуємо наступні експериментальні методи: оптичні (цифрова та конфокальна мікроскопія), електрофізіологічні (мікроелектроди, іонофорез, петч-клемп), генетичні (трансфекція, інфекція, сайт-специфічний мутагенез) та математичні(математичне моделювання, математична статистика).</div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>−</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Лабораторія Молекулярної Біофізики була заснована в квітні 2012 року на базі дослідницької групи відділу [Department of General Physiology of Nervous System|Загальної Фізіології Нервової Системи], яка була керована Павлом Біланом. Головними предметами досліджень протягом останніх років були механізми регуляції внутрішньоклітинної концентрації Ca2+та кальцієва сигналізації в різних типах збудливих клітин.В експериментах використовуються нейрони, які є ізольованими або знаходяться в культурі, а також зрізи мозкута інтактний спинний мозок.В наших дослідженнях ми застосовуємо наступні експериментальні методи: оптичні (цифрова та конфокальна мікроскопія), електрофізіологічні (мікроелектроди, іонофорез, петч-клемп), генетичні (трансфекція, інфекція, сайт-специфічний мутагенез) та математичні(математичне моделювання, математична статистика).</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Дослідження'''==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=='''Дослідження'''==</div></td></tr>
</table>Amor