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{{righttoc}} ====Education==== * Donetsk University, Faculty of Physics, M.S. in Biophysics, 1965-1970. * Postgrad. student, A.A.Bogomoletz Institute of Physiology, 1972-1975 (Thesis supervisor Prof.P.G.Kostyuk), 1976 Ph.D; * Doctor of Biology, 1985. ====Visiting Position==== * Visiting Professor, Department of Physiology, Iwate Medical University, Morioka, Japan; March - June, 1990. * Postdoctoral scientific researcher, Centre for Neurobiology and Behavior, Columbia University, New York, USA; 1996-1998 ====Permanent professional affiliation==== :O.O.Bogomoletz Institute of Physiology :Departmet of General Physiology of Nervous System :Bogomoletz str., 4 :Kiev - 24, GSP 252601, Ukraine :Fax: 380 44 293-34-31; :E-mail: nik@serv.biph.kiev.ua ====Position==== Leading scientific researcher ====Editorial Board==== [[Journals|Neurophysiology]] ====Membership==== * New York Academy of Sciences * [http://www.sfn.org/ Society for Neuroscience] ==Research Interests== * Cellular mechanisms of plasticity; * Pacemaker activity and neuropeptides; * Regulation of calcium current; * Relationship between electrical processes in surface membrane and biochemical reactions in cytoplasm; * Membrane properties of identified molluscan neurons; * Current and voltage clamp; * Patch-clamp; * Intracellular ionophoretic and pressure injection; * Culturing of both neuron and glial cells; * Peptide neurochemistry; ==Publications== #Kononenko N.I., Kostyuk P.G., Shcherbatko A.D. Properties of cAMP-induced transmembrane current in mollusk neurons. Brain Res. 376 , pp.239-245, 1986. #Kononenko N.I., Osipenko O.N. A study of the connection between the interneuron initiating pacemaker activity in a bursting neuron and the bursting neuron of the snail Helix pomatia. Cell. and Mol. Neurobiol. 6 , pp.177-190, 1986. #Kostyuk P.G., Kononenko N.I., Shcherbatko A.D. cAMP-activated ionic channels in the nerve cell membrane. In: "Receptors and Ion Channels". Ed. Y.A.Ovchinnikov and F.Hucho, 1987, Walter de Gruyter & Co., Berlin-New York, pp.141-148. #Kononenko N.I. Molluscan neurobiology in the USSR. In: "Neurobiology. Molluscan models". Ed. H.H.Boer, W.P.M.Geraerts and J.Joosse, 1987, North-Holland Publishing Company, Amsterdam/Oxford/New York, pp.158-168. #Kononenko N.I., Osipenko O.N. Inhibition of an identified snail postsynaptic neuron evoked by stimulation of a peptidergic interneuron initiating bursting pacemaker activity in another neuron. Neuroscience, 34 , pp.189-201, 1990. #Koval L.M., Kononenko N.I., Yavorskaya E.N. Histochemical investigation of serotonin-stimulated adenylate cyclase activity in cultured neurons of snail. Neurosci. Res. Comm. 7 , pp.133-139, 1990. #Kononenko N.I., Shcherbatko A.D. The effect of oxytocin on potential-dependent calcium current in snail neurons, Helix pomatia. Comp. Biochem. Physiol. 98C , pp.281-286, 1991. #Kolchinskaya L.I, Kononenko N.I., Pogorelaya N.Ch. Inhibition by oxytocin of voltage-activated calcium influx in cultured PC12 pheochromocytoma cells. Ibid., pp.287-290. #Kononenko N.I. Role of exogenous and endogenous factors in bursting activity of a snail neuron. In: "Studies in Neuroscience. V. 13. Simpler nervous systems" Ed. D.A.Sakharov and W.Winlow, 1991, Manchester University Press, Manchester and New York, pp.270-289. #Kononenko N.I., Shcherbatko A.D. Intrinsic mechanisms of plasticity of a snail nerve cell. In: "Studies in Neuroscience. V. 15. Signal molecules and behaviour" Ed. W.Winlow, D.V.Vinogradova and D.A.Sakharov, 1991, Manchester University Press, Manchester and New York. #Kononenko N.I., Storozhuk M.V. Dopamine inhibits transmission between the interneuron initiating pacemaker activity in a bursting neuron and the bursting neuron of the snail Helix pomatia. Comp. Biochem. Physiol. 102C , pp.17-22, 1992. #Kononenko N.I. Role of cyclase system in generation of pacemaker activity in fast and slow bursters in snail, Helix pomatia. Comp. Biochem. Physiol., 104C , pp.175-180, 1993. #Storozhuk M.V., Kostyuk P.G., Kononenko N.I. Patch-clamp recording of cAMP-induced membrane current noise in Helix pomatia neurons. Neurosci. Lett. 154 , pp.203-205, 1993. #Koval L.M., Kononenko N.I., Lutsik M.D., Yavorskaya E.N. Electron cytochemical study of carbohydrate components in cultured nerve and glial cells of snail Helix pomatia . Comp. Biochem. Physiol. 106A , pp.95-107, 1993. #Koval L.M., Kononenko N.I., Yavorskaya E.N. Electron cytochemical study of carbohydrate components in growth cone of cultured nerve cells of snail Helix pomatia . Comp. Biochem. Physiol. 106A , pp.109-119, 1993. #Kononenko N.I. Mechanism of membrane potential oscillation in bursting neurons of the snail, Helix pomatia (With an Appendix by N.I.Kononenko and E.E.Saftenku). Comp. Biochem. Physiol. 106A pp.135-147, 1993. #Kononenko N.I. Dissection of a model for membrane potential oscillations in bursting neuron of snail, Helix pomatia . Comp. Biochem. Physiol. 107A , pp.323-332, 1994. #Kononenko N.I. Mathematical model of pacemaker activity in bursting neurons of snail. In: Proceeding of the IMACS Symp. on Mathematical Modelling. Vienna, 315-318, 1994. #Koval L.M., Kononenko N.I., Lutsik M.D., Yavorskaya E.N. Electron cytochemical study of carbohydrate components in different types of cultured glial cells of snail Helix pomatia. Comp. Biochem. Physiol. 108A , pp.195-212, 1994. #Komendantov A.0., Kononenko N.I. Chaos in mathematical model of pacemaker activity in bursting snail neuron. Systems Analysis Modelling Simulation, 18-19 , pp.725-728, 1995. #Komendantov, A.O. and Kononenko, N.I. Deterministic chaos in pacemaker neurons of snail: experiment, model and simulation (Abstract. 40th Annual Meeting of Biophysical Society, Baltimore, Maryland). Biophys. J. 1996, vol. 70, N2(2), A409 . #Komendantov, A.O., Kononenko, N.I. Deterministic chaos as a neuronal correlate of brain functions. Conference: Toward a Science of Consciousness 1996 "Tucson II", April 8-13, Arizona (In: Consciousness Research Abstracts (Tucson II), Imprint Academic, 192pp). #Berezetskaya N.M., Kharkyanen V.N., Kononenko N.I. Mathematical model of pacemaker activity in bursting neuron of snail, Helix pomatia. J.Theor.Biol. 183, pp.207-218, 1996. #Komendantov A.O., Kononenko N.I. Deterministic chaos in mathematical model of pacemaker activity in bursting neurons of snail, Helix pomatia. J.Theor.Biol. 183, pp.219-230, 1996. #Komendantov, A.O., Kononenko, N.I. Route to chaos, crisis and oscillatory mode transition in a model neuron. Proceedings of the International Conference: Nonlinearity, Bifurcation, Chaos: The Doors To The Future. September 16-18, 1996, Lodz-Dobieskow, Poland, pp.149-152. #Komendantov, A.O. and Kononenko, N.I. Roles of [Ca2+]in-activated non-selective cation channels in oscillatory activity of nerve cell: model studies. (Abstract.41th Annual Meeting of Biophysical Society, New Orleans, Louisiana) Biophys. J. 1997, vol.72, N 2(2), A366. # Grishchenko O.V., Kharkyanen V.N., Kononenko N.I. and Weinreb G.E. Ion regulation of the kinetics of potential-dependent potassium channels. J. Biol. Physics 23, pp. 195-208, 1997. # Kononenko N., Hawkins R.D. PTP at Aplysia sensory-motor neuron synapses in isolated cell culture does not involve NMDA receptors or nitric oxide signaling. Abstracts: Society for Neuroscience, 28th Annual Meeting, Los Angeles, Calif., November 7-12, 1998, p.1189 (Part 1). #Kononenko N.I. Role of the axodendritic tree in the functioning of Helix bursting neurons: generation of pacemaker activity and propagation of action potentials along the axon. Neuroscience 96, pp.399-406, 2000.

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